Guardian Connect
Medtronic Simplera Sync
Summary
The Medtronic Guardian Connect is a continuous glucose monitoring (CGM) system that provides real-time glucose data on a compatible smartphone. The system offers optional low and high blood sugar notifications and can be inserted on the abdomen or back of the upper arm.
MARD of 9.6%
This is a disposable, all-in-one CGM sensor integrated with Medtronic’s pump systems (e.g., MiniMed 780G). Typical wear time is 6 days, plus a 24-hour “grace period.” No routine fingersticks are required when the device is in closed-loop/SmartGuard mode.
FDA approved for ages 7+ on the back of the upper arm
MARD of ~9%
Components
Receiver
Trends and alerts are viewed directly on a mobile device. Available for both iOS and Android devices.
Transmitter
Seashell-shaped with built-in Bluetooth capability that allows it to send glucose data directly to a smartphone every 5 minutes.
Sensor
Sensor is inserted underneath the skin, either on the abdomen or arm. Push buttons applicator allows sensor to be placed on the body in one step.
Sensor
Sensor uses a thin, flexible filament beneath the skin to continuously measure glucose every 5 minutes. Simple, one-step applicator makes insertion fast and easy.
Device Details
Overview
One of the larger sensors, may be cumbersome to wear on some parts of the body under clothes.
Disposable, all-in-one CGM sensor integrated with Medtronic’s pump systems
Affordability and Access
$$$$
Sometimes covered. The costs vary depending on individual insurance coverage and how insurance classifies CGMs. Price range $0-$600/month.
$$$$
Coverage depends on region and insurance; supplied via DME or specialty pharmacy.
Data Monitoring Options
Yes
CGM data can be linked to a CareLink account and shared with the user's health care team.
Yes
Data streams directly to the pump; users and clinicians can view trends and logs via Medtronic’s platforms.
Data View Options
Yes
The Guardian Connect mobile app allows users to view glucose levels, trends, create customizable alerts, and share blood glucose data with family and friends.
Yes
Data view directly on your connected pump or smart device.
Duration and Storage
7 Days
Sensors last 7 days, and transmitter battery needs weekly charging and replacement once a year. Both can be stored between 36°F - 86°F.
6 Days
Sensors last 6 days, with a 24-hour grace period, and need about 2 hours to warm up. They work between 41°F – 104°F and should be stored between 36°F – 86°F. They are usually shipped in 1–3 month supplies, which is about 5–15 sensors at a time.
Vision / Auditory / Dexterity
YES text to speech
YES vibration alerts
A LOT of dexterity needed
YES text to speech
YES vibration alerts
Multiple sound sources
Moderate dexterity needed
Patient Considerations
Active Lifestyle
Waterproof transmitter when submerged in up to 2.5 meters of water for 30 minutes and must be within 20 feet of a connected mobile device.
Compact and integrated. Reducing bulk; compatibility with daily activities depends on the adhesive and body movement. Water-resistant up to 8 feet (2.4 m) for 30 minutes.
Avoiding Highs and Lows
Measures sensor glucose 24/7 and sends alerts when a high or low is detected. Trend arrows show the direction glucose is heading, with the rate of change.
SmartGuard closed-loop. Pump adjustments use sensor data continuously to reduce highs and lows.
Comfort
More tape is needed for Medtronic sensors.
Low profile. No overtape needed and one-hand insertion.
Easy Insulin Dosing
Sensor trends can be used for dose adjustment.
SmartGuard technology. When paired with the MiniMed 780G, it automatically adjusts basal and gives correction boluses based on sensor readings. In manual mode, glucose values can guide dosing decisions, but fingersticks are required for confirmation.
Easy to Use
Rechargeable sensor transmitter but has the most steps to change sensor.
All-in-one. Eliminates the need for a separate transmitter, simplifying sensor changes (although more frequent due to the 6-day wear).
Fewer Fingersticks
2 daily finger-sticks are needed to calibrate the sensor.
Calibration is optional. Perfect if you like having that choice.
Privacy
Somewhat discreet. Ability to see sugar on watch or phone. Sensor requires regular meter use.
Small and integrated, but visible on the back of the arm. No separate transmitter reduces the number of visible parts. Alerts and alarms can be adjusted for discretion.