twiist
MiniMed Flex
Summary
The twiist AID system was cleared by the FDA for use with CGMs that have received FDA designation as integrated continuous glucose monitors (iCGMs). As the twiist AID system gets closer to commercial availability, Sequel Med Tech will publicize the list of compatible CGM
*Recently FDA approved for people with type 1 diabetes ages 6 and up.
The MiniMed Flex is a tubed insulin pump system designed to automate insulin delivery using SmartGuard™ technology and the Simplera Sync sensor. Boluses can be delivered directly through the MiniMed app, while customizable settings help support glucose management throughout the day.
Components
Infusion Set
An infusion set contains the thin plastic tubing that delivers insulin from the pump to the body.
Controller
Pump is controlled by the twiist app on an iPhone. Data from both the pump and CGM are viewable on the twiist app Home Screen.
Pump
Pump can be worn with a pump clip, adhesive patch or in a pocket.
Controller
Pump receives CGM readings and automatically adjusts insulin delivery. Data from the pump and CGM viewable on compatible smartphones.
Infusion Set
An infusion set contains the thin plastic tubing that delivers insulin from the pump to the body. Optional Medtronic Extended™ Infusion set (up to 7-day wear) available.
Reservoir
Tubed insulin pumps contain a plastic reservoir or cartridge that is manually filled with insulin and locked into the pump. ExtendedTM Reservoir MMT-342, 10PK. 3.0 ml (300 units).
Pump
Pump connects tubing to a small patch called an infusion set that attaches to the body.
Device Details
Overview
This system automatically adjusts insulin delivery according to continuous glucose monitor (CGM) readings and predicted blood sugar levels. It is the first FDA-approved AID system with Apple Watch compatibility.
A tubed insulin pump system that works with the Simplera Sync sensor and SmartGuard™ technology to automatically adjust insulin delivery.
Affordability and Access
$$$$
No insurance coverage data. Anticipated to be provided through Pharmacy.
Widely covered for insulin-dependent type 1 and type 2. Pump can be provided by pharmacy or DME. Price range; $0-$8,574 to start and $0-$300/Month. Price range varies depending on insurance coverage.
Data Monitoring Options
Yes
Compatible with Tidepool - a web-based diabetes data management system.
Yes
Pump data can be viewed by your healthcare team on the CareLink therapy management software.
Data View Options
Yes
Data is stored and can be viewed directly from the twiist app on the mobile device (iPhone), and can be linked to an Apple Watch for viewing data as well.
Yes
Data is viewed on the phone app.
Duration and Storage
3-day pump 10-day sensor
Sensors last 10 days, and transmitters last 90 and work at 50ºF – 108ºF. The reservoir holds 300 units and is disposable, and the pump can be used for up to 3 years.
2-3 Days. Infusion site and pump reservoir last up to 72 hours and works between 41ºF - 93ºF.
Vision / Auditory / Dexterity
YES text to speech
YES vibration alerts
A LOT of dexterity needed
NO text to speech
YES vibration alerts
A LOT of dexterity needed
Patient Considerations
Active Lifestyle
Waterproof. The pump, when connected to the cassette, has a rating of IP28, indicating protection from continuous immersion in water. The pump can tolerate immersion to depths of up to 12 feet (3.7 m) for 1 hour.
Exercise mode. Optional settings for exercise to adjust treatment ranges for activity with the press of a button. Pump is waterproof for up to 8 feet for 105 minutes.
Avoiding Highs and Lows
Automatically adjusts insulin delivery. Increases or decreases insulin delivery to meet glucose targets. Insulin delivery settings can be aggressive or conservative.
Precise dosing. Pumps allow different amounts of basal insulin at different times of day and very precise dosing.
Comfort
Low-profile. Low profile with an adhesive design that prevents the pump from catching on other objects.
Small tubed pump. Small patch called an infusion set consists of a complete tubing system that attaches to the body. Tubed pumps have the most infusion sets to pick from.
Easy Insulin Dosing
Customizable. Can bolus from phone, smartwatch, or directly from the device without needing to be attached to your phone. The device also directly measures the volume (amount) and flow (speed) of insulin delivered with every micro-dose
Customizable dosing. Bolus calculator available to help figure out doses. Basal and bolus in 0.05 increments.
Easy to Use
Watch compatible. The twiist AID system is the first FDA-approved AID system that can be directly controlled from an Apple Watch.
Pump has a rechargeable battery that takes 30 minutes to charge, and lasts about a week.
Fewer Fingersticks
Factory-calibrated sensor. Fingersticks needed for backup only.
Frequent fingersticks are still required.
Privacy
Discreet. The pump is in two pieces - the top (algorithm and battery) and the bottom (insulin chamber and AVS technology)
Discrete. The MiniMed Flex is small with visible tubing. Can be clipped to clothing or placed in a pocket to be discrete when needed.