twiist
Instinct sensor, made by Abbott, for MiniMed 780G
Summary
The twiist AID system was cleared by the FDA for use with CGMs that have received FDA designation as integrated continuous glucose monitors (iCGMs). As the twiist AID system gets closer to commercial availability, Sequel Med Tech will publicize the list of compatible CGM
*Recently FDA approved for people with type 1 diabetes ages 6 and up.
This is a CGM sensor made by Abbott, exclusively designed for MiniMed 780G system. It will work with MiniMed 780G and related systems. Wear time is up to 15 days, and warm-up is ~1 hour. Fingersticks are not required in closed-loop mode.
FDA approved for ages 7+ for use on the upper arm (back of upper arm)
MARD of ~8.5%
Components
Infusion Set
An infusion set contains the thin plastic tubing that delivers insulin from the pump to the body.
Controller
Pump is controlled by the twiist app on an iPhone. Data from both the pump and CGM are viewable on the twiist app Home Screen.
Pump
Pump can be worn with a pump clip, adhesive patch or in a pocket.
Sensor
Sensor uses a thin, flexible filament beneath the skin to continuously measure glucose every 5 minutes. Simple, one-step applicator makes insertion fast and easy.
Device Details
Overview
This system automatically adjusts insulin delivery according to continuous glucose monitor (CGM) readings and predicted blood sugar levels. It is the first FDA-approved AID system with Apple Watch compatibility.
Compact all-in-one sensor sensor, made by Abbott, exclusively designed for MiniMed 780G system.
Affordability and Access
$$$$
No insurance coverage data. Anticipated to be provided through Pharmacy.
$$$$
Coverage will depend on insurance policies and Medtronic’s rollout plan
Data Monitoring Options
Yes
Compatible with Tidepool - a web-based diabetes data management system.
Yes
Data streams directly to the pump; users and clinicians can view trends and logs via Medtronic’s platforms.
Data View Options
Yes
Data is stored and can be viewed directly from the twiist app on the mobile device (iPhone), and can be linked to an Apple Watch for viewing data as well.
Yes
Data view directly on your connected pump or smart device.
Duration and Storage
3-day pump 10-day sensor
Sensors last 10 days, and transmitters last 90 and work at 50ºF – 108ºF. The reservoir holds 300 units and is disposable, and the pump can be used for up to 3 years.
15 Days
Sensors last up to 15 days and need about 1 hour to warm up. They work between 50ºF – 113ºF and should be stored between 36ºF – 82ºF. They are usually shipped in 1–3 month supplies, which is about 2–6 sensors at a time.
Vision / Auditory / Dexterity
YES text to speech
YES vibration alerts
A LOT of dexterity needed
YES text to speech
YES vibration alerts
Multiple sound sources
SOME dexterity needed
Patient Considerations
Active Lifestyle
Waterproof. The pump, when connected to the cassette, has a rating of IP28, indicating protection from continuous immersion in water. The pump can tolerate immersion to depths of up to 12 feet (3.7 m) for 1 hour.
Long wear & water resistant. Longer wear reduces change burden; sensor design aims for robustness with movement. Water-resistant up to 3 feet (1 m) for 30 minutes (same standard as FreeStyle Libre family).
Avoiding Highs and Lows
Automatically adjusts insulin delivery. Increases or decreases insulin delivery to meet glucose targets. Insulin delivery settings can be aggressive or conservative.
Continuous closed-loop insulin adjustment helps maintain tighter control.
Comfort
Low-profile. Low profile with an adhesive design that prevents the pump from catching on other objects.
Small & Discreet. Very small, discreet form factor, and minimal bulk.
Easy Insulin Dosing
Customizable. Can bolus from phone, smartwatch, or directly from the device without needing to be attached to your phone. The device also directly measures the volume (amount) and flow (speed) of insulin delivered with every micro-dose
MiniMed 780G closed-loop algorithm: adjusts basal and delivers automatic correction boluses using sensor data. Longer wear (15 days) means fewer interruptions in automated dosing. In manual mode, it still requires fingerstick confirmation before dosing from sensor values.
Easy to Use
Watch compatible. The twiist AID system is the first FDA-approved AID system that can be directly controlled from an Apple Watch.
Longer sensor life and shorter warm-up (~1 hour) help with convenience.
Fewer Fingersticks
Factory-calibrated sensor. Fingersticks needed for backup only.
Factory-calibrated sensor. Finger sticks needed for backup only.
Privacy
Discreet. The pump is in two pieces - the top (algorithm and battery) and the bottom (insulin chamber and AVS technology)
Small & Customizable. Extremely small (about the size of two stacked pennies), designed to be less noticeable under clothing. Upper arm site only; discreet but still visible with sleeveless clothing. Alerts can be customized on the connected pump for quieter use.