Medtronic Simplera Sync
DIY Loop
Summary
This is a disposable, all-in-one CGM sensor integrated with Medtronic’s pump systems (e.g., MiniMed 780G). Typical wear time is 6 days, plus a 24-hour “grace period.” No routine fingersticks are required when the device is in closed-loop/SmartGuard mode.
FDA approved for ages 7+ on the back of the upper arm
MARD of ~9%
Loop is a DIY (do-it-yourself) system. It takes some work to set up but allows people to think about diabetes less by automating basal insulin delivery based on predicted glucose levels. This system can be used with the Dexcom G6 and the Omnipod or Medtronic pumps. Information about DIY Loop can be found on the Loop or Riley Link websites.
Components
Sensor
Sensor uses a thin, flexible filament beneath the skin to continuously measure glucose every 5 minutes. Simple, one-step applicator makes insertion fast and easy.
Controller
Smartphone or smartwatch receives CGM readings and automatically adjusts insulin delivery via an Omnipod or Medtronic pump.
Transmitter
RileyLink allows the pump and sensor to communicate. It is only required if a Medtronic pump is used.
Sensor
Automatic applicator inserts sensor just under the surface of the skin and can be applied to many places on the body.
Pump
The system is compatible with Omnipod (left) or Medtronic (right) pumps. Both options can be applied anywhere on the body that is comfortable.
Device Details
Overview
Disposable, all-in-one CGM sensor integrated with Medtronic’s pump systems
This is a DIY (do-it-yourself) system that needs significant setup. It has the most flexibility in settings and device options. It also depends on a third device called a "Riley Link" to communicate between sensor, phone, and pump.
Affordability and Access
$$$$
Coverage depends on region and insurance; supplied via DME or specialty pharmacy.
$$$$
Supplies can be covered for Omnipod or Medtronic pumps and Dexcom. Price range; $0-$8,574 to start and 0-$300/month. iPhone, app, and Riley link are not covered and must be set up independently. Riley link price range; $135-$165.
Data Monitoring Options
Yes
Data streams directly to the pump; users and clinicians can view trends and logs via Medtronic’s platforms.
Yes
Compatible with Tidepool - a web-based diabetes data management system.
Data View Options
Yes
Data view directly on your connected pump or smart device.
Yes
Data can be viewed on an iPhone.
Duration and Storage
6 Days
Sensors last 6 days, with a 24-hour grace period, and need about 2 hours to warm up. They work between 41°F – 104°F and should be stored between 36°F – 86°F. They are usually shipped in 1–3 month supplies, which is about 5–15 sensors at a time.
3-day pump 10-day sensor
Sensors last 10 days and transmitters last 90, and work at 50ºF – 108ºF. Pods or pump reservoirs last for up to 72 hrs and work from 40ºF – 104ºF.
Vision / Auditory / Dexterity
YES text to speech
YES vibration alerts
Multiple sound sources
Moderate dexterity needed
NO text to speech
YES vibration alerts
A LOT of dexterity needed
Patient Considerations
Active Lifestyle
Compact and integrated. Reducing bulk; compatibility with daily activities depends on the adhesive and body movement. Water-resistant up to 8 feet (2.4 m) for 30 minutes.
Automatic responses. Can set custom blood sugar targets and insulin and carb sensitivities based on type of activity. App automatically responds to blood sugar changes during activity. *Medtronic option is not waterproof. Omnipod option is fully waterproof.
Avoiding Highs and Lows
SmartGuard closed-loop. Pump adjustments use sensor data continuously to reduce highs and lows.
Automatically adjusts insulin delivery. Increases or decreases insulin delivery to meet glucose targets. Insulin delivery settings can be aggressive or conservative.
Comfort
Low profile. No overtape needed and one-hand insertion.
Low-profile but extra device. Low profile/low maintenance sensor. The RileyLink is an extra device that must be carried.
Easy Insulin Dosing
SmartGuard technology. When paired with the MiniMed 780G, it automatically adjusts basal and gives correction boluses based on sensor readings. In manual mode, glucose values can guide dosing decisions, but fingersticks are required for confirmation.
All settings are completely customizable. Can bolus from phone or smartwatch. Can operate “open-loop” where the user must enact insulin delivery based on recommendations or “closed-loop” where modifications to insulin delivery are automatically delivered.
Easy to Use
All-in-one. Eliminates the need for a separate transmitter, simplifying sensor changes (although more frequent due to the 6-day wear).
Difficult set-up but easy to use. Software makes most dosing decisions. Requires many parts. Can be difficult to set up.
Fewer Fingersticks
Calibration is optional. Perfect if you like having that choice.
Factory-calibrated sensor. Fingersticks needed for backup only.
Privacy
Small and integrated, but visible on the back of the arm. No separate transmitter reduces the number of visible parts. Alerts and alarms can be adjusted for discretion.
Discreet. Ability to give insulin via watch or phone. Ability to check sugar on phone or watch. Alerts available. *Medtronic pump has tubing. Omnipod is most hideable pump option (no tubes or separate controller needed).