Medtronic Simplera Sync
Syringe and Vial
Summary
This is a disposable, all-in-one CGM sensor integrated with Medtronic’s pump systems (e.g., MiniMed 780G). Typical wear time is 6 days, plus a 24-hour “grace period.” No routine fingersticks are required when the device is in closed-loop/SmartGuard mode.
FDA approved for ages 7+ on the back of the upper arm
MARD of ~9%
Traditional syringe and needle. The most affordable insulin delivery option.
Components
Sensor
Sensor uses a thin, flexible filament beneath the skin to continuously measure glucose every 5 minutes. Simple, one-step applicator makes insertion fast and easy.
Needles
Classic syringes with plunger used to fill insulin for injection
Long-acting insulin
Basal (long-acting) insulin vial for steady release of insulin that helps control blood sugar between meals, and overnight.
Rapid-acting insulin
Bolus (fast-acting) insulin vial for meal time or high blood sugar correction.
Device Details
Overview
Disposable, all-in-one CGM sensor integrated with Medtronic’s pump systems
Nothing on the body when not in use but very visible when dosing.
Affordability and Access
$$$$
Coverage depends on region and insurance; supplied via DME or specialty pharmacy.
$$$$
Syringes are available worldwide in pharmacies or DME without prescription. Price Range: $0-$300/month depending on insurance coverage.
Data Monitoring Options
Yes
Data streams directly to the pump; users and clinicians can view trends and logs via Medtronic’s platforms.
No Options
Data View Options
Yes
Data view directly on your connected pump or smart device.
No Options
Duration and Storage
6 Days
Sensors last 6 days, with a 24-hour grace period, and need about 2 hours to warm up. They work between 41°F – 104°F and should be stored between 36°F – 86°F. They are usually shipped in 1–3 month supplies, which is about 5–15 sensors at a time.
28 Days
Open vials can be stored at room temperature (not above 80º F) for up to 28 days. Unopened vials should be stored in the refrigerator (36ºF - 86ºF.)
Vision / Auditory / Dexterity
YES text to speech
YES vibration alerts
Multiple sound sources
Moderate dexterity needed
NO text to speech
NO vibration alerts
A LOT dexterity for insertion
Patient Considerations
Active Lifestyle
Compact and integrated. Reducing bulk; compatibility with daily activities depends on the adhesive and body movement. Water-resistant up to 8 feet (2.4 m) for 30 minutes.
Limited Adjustability. No way to adjust long-acting insulin for higher activity on the fly.
Avoiding Highs and Lows
SmartGuard closed-loop. Pump adjustments use sensor data continuously to reduce highs and lows.
Limited customizability. Requires a high level of engagement and effort to avoid highs and lows but can be paired with a CGM for improved blood sugar control.
Comfort
Low profile. No overtape needed and one-hand insertion.
Many components. Must carry insulin vials and large syringes but nothing attached to the body.
Easy Insulin Dosing
SmartGuard technology. When paired with the MiniMed 780G, it automatically adjusts basal and gives correction boluses based on sensor readings. In manual mode, glucose values can guide dosing decisions, but fingersticks are required for confirmation.
Requires attention. You have to do the math to figure out your dose. Unable to adjust basal in real-time.
Easy to Use
All-in-one. Eliminates the need for a separate transmitter, simplifying sensor changes (although more frequent due to the 6-day wear).
Many steps. Requires effort to figure out doses and deliver insulin every single time you need it.
Fewer Fingersticks
Calibration is optional. Perfect if you like having that choice.
Frequent finger-sticks are required.
Privacy
Small and integrated, but visible on the back of the arm. No separate transmitter reduces the number of visible parts. Alerts and alarms can be adjusted for discretion.
Hideable. Vials and syringes can be hidden when not in use but very visible when in use. Frequent injections are unavoidable.